CRISA is conducting clinical trials to the advancement of medical science

List of Clinical Trials

#Trial NameTherapeutic AreaContact Person
1A 40-week study comparing the efficacy and safety of once weekly IcoSema and daily insulin glargine 100 units/mL in participants with type 2 diabetes inadequately controlled on oral anti-diabetic drugs. COMBINE 4
Start date: 02 April 2024

EndocrinologyNonkqubela Bantubani
nbantubani@crisa.org.za
2A randomised, double-blind, placebo-controlled Multicenter Study to Evaluate the Effect of Inclisiran on Preventing Major Adverse Cardiovascular Events in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke (victorion-i-prevent).
Start date: 06 November 2023
End date: Ongoing
CardiovascularNonkqubela Bantubani
nbantubani@crisa.org.za
3A randomised, Double-Blind, Parallel Design, Repeat Dose, 2-arm, Multicenter Study Comparing the Efficacy, Safety, Immunogenicity, and Pharmacokinetic Profiles of AVT03 and US-Prolia® in Postmenopausal Women with Osteoporosis.
Start date: 06 October 2022
End date: Ongoing
OrthopedicsNonkqubela Bantubani
nbantubani@crisa.org.za
4A randomised, double-blind, placebo-controlled, Phase 1/2 study to evaluate inhaled IBIO123 in participants with mild to moderate COVID-19 illness.
Start date: 05 September 2022
End date: 8 December 2022
Infectious DiseasesNonkqubela Bantubani
nbantubani@crisa.org.za